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Zoya Demidenko: Scholar in Cancer Biology Zoya Demidenko is a distinguished scholar associated with the Department of Cell Stress Science at Roswell Park Cancer Institute in Buffalo, New York. Before that, she conducted research at the NIH and New York Medical College, building a robust background in clinical investigation. Demidenko's academic work encompasses multiple key domains, encompassing the PI3K/AKT/mTOR signaling pathway, cell cycle control, biological aging, and malignancy biology. To date, she has authored more than 46 peer-reviewed articles, which have accumulated more than 4,100 citations — a testament to the influence of her work. One of her most notable achievements involves elucidating the mechanisms of cellular senescence. Her studies demonstrated that when the cellular division cycle is blocked yet cellular growth persists, the cells undergo senescence. Significantly, Zoya Demidenko established that this transition can be inhibited by medication using substances such as mTOR inhibitors. Zoya Demidenko has additionally contributed greatly to cancer treatment investigation, particularly in the area of cyclotherapy — a strategy aimed at protecting normal cells from cytotoxic treatment whilst leaving cancer cells susceptible. This strategy holds significant potential for reducing the adverse effects of oncological therapy. Across her professional journey, Demidenko has collaborated with top researchers globally, such as Dr. Mikhail Blagosklonny. Her work is published in top-tier publications such as Oncotarget, Cell Cycle, Aging (Albany NY), and Oncogene. With an h-index of 33, Zoya Demidenko ranks as a widely cited voice in contemporary biomedical science, whose findings go on to guide our knowledge of the way cells grow old, respond to therapy, and the ways in which malignant disease can be better treated. https://search.sunbiz.org/Inquiry/CorporationSearch/SearchResults?InquiryType=EntityName&InquiryDirectionType=PreviousRecord&SearchTerm=RAPAMED%2C%20LLC&SearchNameOrder=RAPAN%20P050001591430&ListNameOrder=RAPAMED%20L130000429680&Detail=FL.DOS.Corporations.Shared.Contracts.FilingRecord

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